Sunday, 14 June 2015

Aldol Reaction

Aldol Addition / Aldol Reaction

Aldol Addition Reaction
 The name ALDOL is taken from Aldehyde and Alcohol.
When the enolate of an aldehyde or a ketone reacts at the α-carbon with the carbonyl of another molecule under basic or acidic conditions to obtain β-hydroxy aldehyde or ketone, this reaction is called Aldol Reaction.

Mechanism of Aldol Reaction

organic chemistry notes - Aldol reaction Mechanism
Aldol Reaction Mechanism - Acid Catalyzed and Base Catalyzed
 If we control kinetic condition for aldol reactions then mixed aldol addition reactions may be used for the preparation of the adducts that can not be obtain selectively.
This method begins with irreversible production of  kinetic enolate, for example by employ the sterically or delayed lithium-amide-base like LDA known as lithiumdiisopropylamide and abbreviated as LDA.
named reaction notes


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