Aldol Addition / Aldol Reaction
|Aldol Addition Reaction|
Mechanism of Aldol Reaction
|Aldol Reaction Mechanism - Acid Catalyzed and Base Catalyzed|
If we control kinetic condition for aldol reactions then mixed aldol addition reactions may be used for the preparation of the adducts that can not be obtain selectively.
This method begins with irreversible production of kinetic enolate, for example by employ the sterically or delayed lithium-amide-base like LDA known as lithiumdiisopropylamide and abbreviated as LDA.